
Release Alert: HPE and NVIDIA Revolutionize AI Infrastructure with New ProLiant Servers and Private Cloud AI
HPE and NVIDIA announced a significant advancement in enterprise AI infrastructure, bringing to market HPE ProLiant Compute servers powered by NVIDIA RTX PRO 6000 Blackwell Server Edition GPUs, now also in a compact 2U form factor. This new addition integrates with HPE Private Cloud AI, expanding the ability of enterprises to develop and deploy advanced generative, agentic, and physical AI models faster and more securely.
New Servers to Power AI Workloads
HPE ProLiant DL385 Gen11 (2U, up to 2 NVIDIA RTX PRO 6000 Blackwell GPUs) Ideal for data centers that require efficiency and performance in a small footprint.
HPE ProLiant Compute DL380a Gen12 (4U, up to 8 GPUs) Robust configuration for large-scale AI workloads, available September 2025.
Performance and Security Advantages:
Multi-layered security with HPE Integrated Lights Out (iLO) 7 and quantum-resistant protection.
Cloud-native automation with HPE Compute Ops Management, reducing server management time by up to 75%.
HPE Private Cloud AI with Nvidia GPUs – Ready-to-Use Enterprise AI
The next generation of HPE Private Cloud AI brings deep integration with the NVIDIA AI Enterprise platform and support for:
NVIDIA Nemotron models → agentic AI.
Cosmos Reason (VLM) → physical and robotic AI.
Blueprint VSS 2.4 → video search and summarization with intelligent analytics.
With this solution, companies can:
✅ Rapidly deploy NVIDIA NIM microservices
✅ Manage AI in air-gapped environments
✅ Meet AI inference demands with scalability and complete data control
📅 Availability:
HPE ProLiant servers with NVIDIA RTX PRO 6000 Blackwell GPUs → orders now open, deliveries starting September 2, 2025.
New HPE Private Cloud AI features → second half of 2025.
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